Helping Huge and tiny companies scale their product for market with a new generation of innovative SynBio manufacturing @SolarBioProcessingLLC

I Co-founded IndieBio, the world’s first Synthetic Biology accelerator devoted to funding and building startups dedicated solving humanity’s most pressing problems through biology. Funded more than 70 iconic biotech companies to a market cap of > $500M in 3 years.

Berkeley BioLabs is the first of a new breed of biotech incubators. Founded on the ethos of the DiyBio movement: one person one idea to the bench in weeks not months for hundreds not tens of thousands of dollars.

2004 ­ PresentNetAffx has long been the most successful software project in the company. It isresponsible for receiving 40% of the total traffic to Affymetrix.com and is on the path foruse by each customer practically every time they use the product.Implementation of Axiom custom web application 2.0· Completion of web application for interactive custom product design of our highest revenue product line. The top corporate goal for 2011, the custom design web app was designed together with marketing, web designers and data analysts.· Implementation of a fully functional Ajax UI.· Includes development of middleware that stores customer designs and product information, routing them through data services at multiple locations.Implementation of Axiom custom web application 1.5· Delivery of highly secure file exchange web interface online custom product design in 6 weeks.· Demo of an online data appliance prototype to serve the application queries, capable of looking up a million terms in less than 30 seconds.Scaling of the Netaffx Data Layer· Implementation and oversight of data server transitions through four generations of storage technologies from SRS (flat file server), SQL Server, MySQL, and binary retrieval indexes.· Adoption of binary flat file technology to our data stack to scale for 500-fold speed improvements in our search application.· Expansion of web service from one to three major product lines and 1000-fold increase in data volume without expanding team.

· Design, implementation and maintenance of back end data pipeline, processes 2 terabytes of input from 40+ sources covering 35 different organisms.· Leveraged open source software to reduce licensing operations overhead to zero expenses.· Establishment of quality checks and automation for content pipeline, reduced back end run times from 2 months to 3 weeks.Managing daily web operations· Oversight of team of four to six engineers and scientists with responsibilities that included web portlet operations and content/data pipeline.· Maintenance of operations stack for web application including redundant web servers, data servers and application servers which process customer data for their session.· Support NetAffx services delivering to individual customers and more than a dozen different software solutions, internal and 3rd party.· Computational environment includes use of computational culuster (PBS and LSF) integrated into content creation for NetAffx.· Group responds to daily communication with customers to resolve technical questions and issues.

Major accomplishments in italics)Implemented AxiomTG custom web application 2.0 Working with marketing, web designers and data analysts, implementation of second generation web application for custom product design for our highest revenue product line. Current methods to produce secure interactive Ajax UI.Implemented Axiom TG custom web application 1.5Team delivered simple but highly secure file exchange web interface to initiate online custom design product operation in 6 weeks. Scaling NetAffx Data Layer Revised data retrieval to scale for 500-fold speed improvements.Expanded web service for three major product lines and 1000 fold increase in content without expanding team.Management day to day operations of NetAffx data portal Managed team of four to six engineers and scientists including web portlet operations and content/data pipeline. NetAffx has long been the most successful software in the company. Our section of the site receives 40% of the total traffic to Affymetrix.com and is on the path for use by each customer practically every time they use the product. Integration of NetAffx services to multiple desktop software solutions, internal and 3rd party. Daily communication with customers to resolve technical questions. Leveraged open source software to reduce operations overhead to meet expense goals of zero licensing expenses.Established quality checks and automation for content pipeline.

Biomatica's technology brings 'fail fast' methodology to pharmaceutical development. Early detection of adverse effects allows the pipeline to discover safer drugs even while saving lab-years in development costs.

Reagent Stock Management, promoter sequence evaluation, bacterial genomics.

gene characterization. Developed applications to identify novel gene function in newly sequenced genomes. (patents granted). Developed multiple applications targeted at customer interests to promote new products. (papers and patent resulted). Participated in hardware selection/build, networking, and 24/7 operations for web operations.

Protein Sequence analysis.

Diabetes and Structural Biology