Isomerase Therapeutics is a drug discovery and development company based in Cambridge, UK, with particular expertise in the discovery and development of optimised microbial natural products. We offer a proven route to develop these hits into drugs via our unique biosynthetic medicinal chemistry services.We offer this bespoke biosynthetic engineering/semi-synthetic chemistry platform and drug discovery and development expertise on a FTE basis to partners looking for more than just a CRO. Isomerase Therapeutics can help you take your chosen natural product from an interesting hit to a high value candidate drug.

Responsible for management of preclinical drug discovery and development teams, budgeting and planning.Project leader on cyclophilin inhibitor (HCV/HBV/HIV) programme.Responsible for outsourcing and analysis of screening and pharmacology, natural product fermentation and isolation.Responsible for Intellectual Property portfolio, general contract management, liaison with academic tech. transfer offices and industrial IP departments, patent filing, prosecution and management.Managed team responsible for natural product compound library generation, screening and quality control.Therapeutic area diligence and publicity through presentation and attendance at international conferences and corresponding authorship of papers.Business development support, including completion of successful in-license and out-license activities.Managed project management team and interdisciplinary preclinical/clinical development team.Member of research management team.Managed IT infrastructure and support.

Responsible for Biotica’s IP portfolio, including writing new patent applications, managing prosecution and maintenance and liaising with IP/tech transfer teams at collaborating pharma/biotech and academic institutions.Responsible for managing all external work on the company’s drug development projects including preparing plans, managing timelines negotiating contracts and liaising with virtual CRO/CMO teams.Member of research management team.

Senior molecular biologist with supervision of a research associate, responsible for bioengineering natural products within a multidisciplinary team.Managed IT infrastructure and support for company.

Postdoctoral molecular biologist, supervising undergraduate and postgraduate students. Liaison and collaboration with industrial partners.