Art Williams Email & Phone Number

Bethlehem, Pa

Providing Informatics and IT strategic planning, business analysis and project/portfolio management for Pharmaceutical and Biotechnology companies. Analyze business situations to determine needs regarding business processes and functionality and make recommendations. Develop project proposals and SOWs, as well as, project resource requirements.

55 Corporate Drive, Bridgewater, Nj

The TSU Immuno-Inflammation is an entrepreneurial unit responsible for all Discovery and Development activities through Phase II. My specific responsibilities are for TSU Electronic Communications (intranet, internet), portfolio tracking and reporting, budget and resource management, and contract management. Scientific responsibilities include providing informatics and computational consulting and support to TSU Discovery and Development teams and interfacing with Technical groups (Scientific Information Systems, Scientific Computing & Data Management and Biostatics) to help provide that support.Major Accomplishments include:• Established a SharePoint environment to run all TSU business – News and Updates, Portfolio Management, Development Project and Discovery Program team sites, External Partner Collaboration sites, Departmental team site, Scientific and Competitive Intelligence Information, Education and Training.• Designed and implemented a computational infrastructure to find alternate indications for portfolio targets.

1041 Route 202-206, P.O. Box 6800, Bridgewater, Nj

Responsible for tracking the scientific portfolio, scientific reporting and global resource management for the Proteins & Target to Lead Biology (PTLB) unit within Biological Sciences (BioS). Additional responsibilities included: overseeing all BioS projects and activities that require support from Scientific Information Systems (SIS), Scientific Computing & Data Management (SCDM) and Biostatistics; as well as developing and managing the BioS portfolio of Informatics projects with SIS and SCDM.Major Accomplishments include:• Established a global project and resource tracking and reporting process for PTLB to enable decision-support.• Oversaw the implementation of several LIMS systems supporting Proteomics, Molecular Pathology, and Biological Sample registration and tracking,

1041 Route 202-206, P.O. Box 6800, Bridgewater, Nj

Appointed Global Head of Bioinformatics for sanofi aventis in January 2005 to direct Bioinformatics across 5 sites and 3 countries (US, France and Germany) supporting 6 Therapeutic Departments on 17 sites in Europe and the US. Responsible for developing and implementing a global Bioinformatics strategy in support of Drug Discovery and Development. Major Accomplishments include:• Created a global Bioinformatics department of 48 FTEs from components of 5 departments in the two previous companies.• Oversaw a systems biology approach for integrating and analyzing biological information and managing knowledge to identify targets, determine biomarkers, mechanism of action and mechanism of toxicity.

1041 Route 202-206, P.O. Box 6800, Bridgewater, Nj

Directed and managed an integrated Informatics organization consisting of the Bioinformatics, Chemoinformatics, Scientific Computing, and Training, Awareness and Utilization (TAU) departments within the US at three locations (Bridgewater, NJ, Cambridge, MA and Tucson, AZ). Developed and managed the operating budget for US Informatics. Managed strategic Informatics alliances and partner relationships. Major Accomplishments include:• Managed the US Informatics department of 34 FTEs and 20 contractors with operating budgets of over $15M.• Responsible for the development and implementation of Informatics Foundation Systems in support of Drug Discovery• Established a Bioinformatics & Biostatistics computational platform for Toxicogenomics in support of Drug Safety• Oversaw the design and evaluation of a prototype method for correlation of structural/chemical features with bio-response profiles

2336 South 12Th St, Suite B, Allentown, Pa

A consulting firm providing Informatics and Information Technology consulting and management services for the Biotechnology and Pharmaceutical Industries. Major engagements included:• Immune Tolerance Network (www.immunetolerance.org) – Acting Director of Informatics and Information Technology, February 2002 to August 2003, responsible for developing an Informatics and IT strategic plan, developing budget plans, issuing and review of RFPs, overseeing subcontractors, project management of ongoing projects, development of an integrated Clinical and Biological repository and data management system, development of a core assay specimen tracking system.• Ivega Corporation – Chief advisor for the Pharmaceutical and Biotechnology practice of Ivega Corporation. Company subsequently merged to form TCG Ivega.• SaintLife Pharmaceutical Research Laboratories - Acting Chief Informatics Officer, August 2002 to July 2003, of an Indian-based Pharmaceutical R&D outsourcing company, responsible for the oversight, development and implementation of Informatics and Information Technology. Company subsequently acquired in August 2004.

450 Sentry Parkway, Blue Bell, Pa

Developed and managed the execution of an Informatics Strategy for Genomics Collaborative, Inc. (GCI). Directed and managed the Bioinformatics, Clinical Data Management, Biostatics, Computing and Networking Systems, and Software Development departments of GCI. Developed and managed the operating budget for Informatics. Ensured that hardware/software/communication performance needs for GCI were met. Ensured that all ethical/regulatory requirements were met regarding patient data and genetic samples.Major Accomplishments include:• Organized and built the Informatics department of 52 FTEs and 20 contractors with operating budgets of over $8M.• Established a scaleable, clinical data management workflow to process over 100K pages of patient data per month.• Developed a data warehouse/datamart model for linking phenotypic/genotypic/chemical/molecular data and information.

Pharmaceutical Research Institute, Bristol-Myers Squibb Company, 1 Squibb Drive,

My primary responsibility was to develop and manage the execution of the Pharmaceutical Development (PD) Information Technology (IT) Strategy and all PD IT investments worldwide. Develop and manage an IT investment portfolio and operating plan for PD. Drive the development and deployment of new business solutions for PD through the strategic use of computing and information technology. Developed and managed an operating budget with the IT Shared Services for all services provided to PD through IT Shared Services. Provided requirements, direction, review and customer satisfaction input to IT Shared Services groups. Managed targeted strategic IT vendor and partner relationships. Major Accomplishments include:• Initiated and built Pharmaceutical Development Informatics to a department of 35 FTEs and 40 contractors with operating budgets of over $10M.• Established an IT portfolio management process for Pharmaceutical Development.• Developed a strategic planning process to support the business needs of Pharmaceutical Development.• Oversaw the Y2K remediation of over 100 applications supporting Pharmaceutical Development• Participated on a corporate-wide e-Business council

709 Swedeland Road, King Of Prussia, Pa

Directed Bioinformatics application/systems development, systems management, computational studies and training activities in support of SB’s worldwide R&D and SB’s genomics business alliance partners. Provide strategic/operational planning, consultation, and advisory services on Computational Genomics and Information Technology for worldwide R&D initiatives and business alliances. Coordinate R&D Scientific & Clinical Systems and Corporate Strategic IT efforts and planning to ensure that the hardware/communication performance needs and specifications for R&D genomics operations worldwide are met. Direct Bioinformatics staff to ensure that all computational, production, development and support activities meet the strategic and future needs of R&D.Major Accomplishments include:• Initiated and expanded the Bioinformatics Systems & Support department from 1 to 32 FTEs and 10 contractors.• Developed, deployed, maintained and supported ATGene (a web-based multi-tierd application) to worldwide SB R&D and three international Alliance Partners (Takeda, Synthelabo, Merck KGaA).• Developed, deployed and maintained CATalyst (a large-scale high-throughput Genomics analysis system).• Integrated, deployed and maintained a worldwide LIMS in support of BioPharmaceutical Research.

709 Swedeland Road, King Of Prussia, Pa

Planned and oversaw the application of advanced computing technologies throughout non-Clinical R&D, working with senior management in R&D to develop broad-based computing strategies, proposed and coordinated the implementation of associated projects in Computing & Information Sciences (C&IS), worked with the drug program/project teams toward resolution of operational issues, ensured equipment and personnel allocations within C&IS were consistent with overall R&D directions, participated in budgeting teams to determine purchase of equipment and software, served as a consultant to R&D staffs, aided R&D staff in the proper and timely tracking, analysis, and reporting of data for the FDA and other regulatory agencies.Major Accomplishments include:• Planned and oversaw the upgrade and conversion of SB R&D network to fiber/ethernet and introduced UNIX systems into the mainstream.• Initiated and oversaw the development of LIMS in Chemical Development and Pharmaceutical Technologies.• Initiated and oversaw the development of a Formulations system.

Ph.D., Biophysical Chemistry

Postdoctoral Research Associate, Computational Molecular Biology

B.S., Chemistry